Blar i forfatter "Tzoulaki, Ioanna"

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    • Alcohol intake in relation to non-fatal and fatal coronary heart disease and stroke: EPIC-CVD case-cohort study 

      Ricci, Cristian; Wood, Angela; Muller, David; Gunter, Marc J.; Agudo, Antonio; Boeing, Heiner; van der Schouw, Yvonne T.; Warnakula, Samantha; Saieva, Calogero; Spijkerman, Annemieke M.W.; Sluijs, Ivonne; Tjønneland, Anne; Kyrø, Cecilie; Weiderpass, Elisabete; Kühn, Tilman; Kaaks, Rudolf; Sánchez, Maria-Jose; Panico, Salavatore; Agnoli, Claudia; Palli, Domenico; Tumino, Rosario; Engström, Gunnar; Melander, Olle; Bonnet, Fabrice; Boer, Jolanda M.A.; Key, Timothy J.; Travis, Ruth C.; Overvad, Kim; Verschuren, W.M. Monique; Quirós, José Ramón; Trichopoulou, Antonia; Papatesta, Eleni-Maria; Peppa, Eleni; Iribas, Conchi Moreno; Gavrila, Diana; Forslund, Ann-Sofie; Jansson, Jan-Håkan; Matullo, Giuseppe; Arriola, Larraitz; Freisling, Heinz; Lassale, Camille; Tzoulaki, Ioanna; Sharp, Stephen J.; Forouhi, Nita G.; Langenberg, Claudia; Saracci, Rodolfo; Sweeting, Michael; Brennan, Paul; Butterworth, Adam S.; Riboli, Elio; Wareham, Nicholas J.; Danesh, John; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-29)
      Objective To investigate the association between alcohol consumption (at baseline and over lifetime) and non-fatal and fatal coronary heart disease (CHD) and stroke.<p> <p>Design Multicentre case-cohort study.<p> <p>Setting A study of cardiovascular disease (CVD) determinants within the European Prospective Investigation into Cancer and nutrition cohort (EPIC-CVD) from eight European ...

    • Comparison of prognostic models to predict the occurrence of colorectal cancer in asymptomatic individuals: A systematic literature review and external validation in the EPIC and UK Biobank prospective cohort studies 

      Smith, Todd; Muller, David C.; Moons, Karel G.M.; Cross, Amanda J.; Johansson, Mattias; Ferrari, Pietro; Fagherazzi, Guy; Peeters, Petra H. M.; Severi, Gianluca; Hüsing, Anika; Kaaks, Rudolf; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Bonet, Catalina; Rodríguez-Barranco, Miguel; Huerta, Jose Maria; Gurrea, Aurelio Barricarte; Bradbury, Kathryn Erica; Trichopoulou, Antonia; Bamia, Christina; Orfanos, Philippos; Palli, Domenico; Pala, Valeria; Vineis, Paolo; Bueno-De-Mesquita, Bas; Ohlsson, Bodil; Harlid, Sophia; Van Guelpen, Bethany; Skeie, Guri; Weiderpass, Elisabete; Jenab, Mazda; Murphy, Neil; Riboli, Eilo; Gunter, Marc J.; Aleksandrova, Krasimira Jekova; Tzoulaki, Ioanna (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-03)
      <i>Objective</i> - To systematically identify and validate published colorectal cancer risk prediction models that do not require invasive testing in two large population-based prospective cohorts.<p><p> <i>Design</i> - Models were identified through an update of a published systematic review and validated in the European Prospective Investigation into Cancer and Nutrition (EPIC) and the UK ...

    • Consumption of meat, fish, dairy products, and eggs and risk of ischemic heart disease: A prospective study of 7198 incident cases among 409 885 participants in the Pan-European EPIC Cohort 

      Key, Timothy J.; Appleby, Paul N.; Bradbury, Kathryn E.; Sweeting, Michael; Wood, Angela; Johansson, Ingegerd; Kühn, Tilman; Steur, Marinka; Weiderpass, Elisabete; Wennberg, Maria; Würtz, Anne Mette Lund; Agudo, Antonio; Andersson, Jonas; Arriola, Larraitz; Boeing, Heiner; Boer, Jolanda M.A.; Bonnet, Fabrice; Boutron-Ruault, Marie-Christine; Cross, Amanda J.; Ericson, Ulrika; Fagherazzi, Guy; Ferrari, Pietro; Gunter, Marc; Huerta, José María; Katzke, Verena; Khaw, Kay-Tee; Krogh, Vittorio; La Vecchia, Carlo; Matullo, Giuseppe; Moreno-Iribas, Conchi; Naska, Androniki; Nilsson, Lena Maria; Olsen, Anja; Overvad, Kim; Palli, Domenico; Panico, Salvatore; Molina-Portillo, Elena; Quirós, J. Ramón; Skeie, Guri; Sluijs, Ivonne; Sonestedt, Emily; Stepien, Magdalena; Tjønneland, Anne; Trichopoulou, Antonia; Tumino, Rosario; Tzoulaki, Ioanna; van der Schouw, Yvonne T.; Verschuren, W.M. Monique; di Angelantonio, Emanuele; Langenberg, Claudia; Forouhi, Nita; Wareham, Nick; Butterworth, Adam; Riboli, Elio; Danesh, John (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-22)
      <i>Background</i> - There is uncertainty about the relevance of animal foods to the pathogenesis of ischemic heart disease (IHD). We examined meat, fish, dairy products, and eggs and risk for IHD in the pan-European EPIC cohort (European Prospective Investigation Into Cancer and Nutrition).<P><P> <i>Methods</i> - In this prospective study of 409 885 men and women in 9 European countries, diet ...

    • Diet quality scores and prediction of all-cause, cardiovascular and cancer mortality in a pan-european cohort study 

      Lassale, Camille; Gunter, Marc J.; Romaguera, Dora; Peelen, Linda M.; van der Schouw, Yvonne T.; Beulens, Joline W.J.; Freisling, Heinz; Muller, David C.; Ferrari, Pietro; Huybrechts, Inge; Fagherazzi, Guy; Boutron-Ruault, Marie-Christine; Affret, Aurélie; Overvad, Kim; Dahm, Christina C.; Olsen, Anja; Roswall, Nina; Tsilidis, Konstantinos K.; Katzke, Verena A.; Kühn, Tilman; Buijsse, Brian; Quirós, José Ramón; Sánchez-Cantalejo, Emilio; Etxezarreta, Nerea; Huerta, José María; Barricarte, Aurelio; Bonet, Catalina; Khaw, Kay-Tee; Key, Timothy J.; Trichopoulou, Antonia; Bamia, Christina; Lagiou, Pagona; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Fasanelli, Francesca; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Boer, Jolanda M.A.; Sonestedt, Emily; Nilsson, Lena Maria; Renström, Frida; Weiderpass, Elisabete; Skeie, Guri; Lund, Eiliv; Moons, Karel G.M.; Riboli, Elio; Tzoulaki, Ioanna (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-07-13)
      Scores of overall diet quality have received increasing attention in relation to disease aetiol- ogy; however, their value in risk prediction has been little examined. The objective was to assess and compare the association and predictive performance of 10 diet quality scores on 10-year risk of all-cause, CVD and cancer mortality in 451,256 healthy participants to the European Prospective ...

    • Diet-wide association study of 92 foods and nutrients and lung cancer risk in the European Prospective Investigation into Cancer and Nutrition study and the Netherlands Cohort Study 

      Heath, Alicia K.; Muller, David C.; van den Brandt, Piet A.; Critselis, Elena; Gunter, Marc; Vineis, Paolo; Weiderpass, Elisabete; Boeing, Heiner; Ferrari, Pietro; Merritt, Melissa A.; Rostgaard-Hansen, Agnetha L.; Tjønneland, Anne; Overvad, Kim; Katzke, Verena; Srour, Bernard; Masala, Giovanna; Sacerdote, Carlotta; Ricceri, Fulvio; Pasanisi, Fabrizio; Bueno-de-Mesquita, Bas; Downward, George S.; Skeie, Guri; Sandanger, Torkjel M; Crous-Bou, Marta; Rodríguez-Barranco, Miguel; Amiano, Pilar; Huerta, José María; Ardanaz, Eva; Drake, Isabel; Johansson, Mikael; Johansson, Ingegerd; Key, Tim; Papadimitriou, Nikos; Riboli, Elio; Tzoulaki, Ioanna; Tsilidis, Konstantinos K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-13)
      It is unclear whether diet, and in particular certain foods or nutrients, are associated with lung cancer risk. We assessed associations of 92 dietary factors with lung cancer risk in 327 790 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC). Cox regression yielded adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) per SD higher intake/day of ...

    • GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification 

      Lagou, Vasiliki; Jiang, Longda; Ulrich, Anna; Zudina, Liudmila; González, Karla Sofia Gutiérrez; Balkhiyarova, Zhanna; Faggian, Alessia; Maina, Jared G.; Chen, Shiqian; Todorov, Petar V.; Sharapov, Sodbo; David, Alessia; Marullo, Letizia; Mägi, Reedik; Rujan, Roxana-Maria; Ahlqvist, Emma; Thorleifsson, Gudmar; Gao, Ηe; Εvangelou, Εvangelos; Benyamin, Beben; Scott, Robert A.; Isaacs, Aaron; Zhao, Jing Hua; Willems, Sara M.; Johnson, Toby; Gieger, Christian; Grallert, Harald; Meisinger, Christa; Müller-Nurasyid, Martina; Strawbridge, Rona J.; Goel, Anuj; Rybin, Denis; Albrecht, Eva; Jackson, Anne U.; Stringham, Heather M.; Corrêa, Ivan R.; Farber-Eger, Eric; Steinthorsdottir, Valgerdur; Uitterlinden, André G.; Munroe, Patricia B.; Brown, Morris J.; Schmidberger, Julian; Holmen, Oddgeir Lingaas; Thorand, Barbara; Hveem, Kristian; Wilsgaard, Tom; Mohlke, Karen L.; Wang, Zhe; Shmeliov, Aleksey; den Hoed, Marcel; Loos, Ruth J. F.; Kratzer, Wolfgang; Haenle, Mark; Koenig, Wolfgang; Boehm, Bernhard O.; Tan, Tricia M.; Tomas, Alejandra; Salem, Victoria; Barroso, Inês; Tuomilehto, Jaakko; Boehnke, Michael; Florez, Jose C.; Hamsten, Anders; Watkins, Hugh; Njølstad, Inger; Wichmann, H.-Erich; Caulfield, Mark J.; Khaw, Kay-Tee; van Duijn, Cornelia M.; Hofman, Albert; Wareham, Nicholas J.; Langenberg, Claudia; Whitfield, John B.; Martin, Nicholas G.; Montgomery, Grant; Scapoli, Chiara; Tzoulaki, Ioanna; Elliott, Paul; Thorsteinsdottir, Unnur; Stefansson, Kari; Brittain, Evan L.; McCarthy, Mark I.; Froguel, Philippe; Sexton, Patrick M.; Wootten, Denise; Groop, Leif; Dupuis, Josée; Meigs, James B.; Deganutti, Giuseppe; Demirkan, Ayse; Pers, Tune H.; Reynolds, Christopher A.; Aulchenko, Yurii S.; Kaakinen, Marika A.; Jones, Ben; Prokopenko, Inga (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-07)
      Conventional measurements of fasting and postprandial blood glucose levels investigated in genome-wide association studies (GWAS) cannot capture the effects of DNA variability on ‘around the clock’ glucoregulatory processes. Here we show that GWAS meta-analysis of glucose measurements under nonstandardized conditions (random glucose (RG)) in 476,326 individuals of diverse ancestries and without ...

    • Nutrient-wide association study of 92 foods and nutrients and breast cancer risk 

      Heath, Alicia K.; Muller, David C.; van den Brandt, Piet A.; Papadimitriou, Nikos; Critselis, Elena; Gunter, Marc; Vineis, Paolo; Weiderpass, Elisabete; Fagherazzi, Guy; Boeing, Heiner; Ferrari, Pietro; Olsen, Anja; Tjønneland, Anne; Arveux, Patrick; Boutron-Ruault, Marie-Christine; Mancini, Francesca Romana; Kuhn, Tilman; Turzanski-Fortner, Renee; Schulze, Matthias B.; Karakatsani, Anna; Thriskos, Paschalis; Thrichopoulou, Antonia; Masala, Giovanna; Contiero, Paolo; Ricceri, Fulvio; Panico, Salvatore; Bueno-De-Mesquita, Bas; Bakker, Marije F.; van Gils, Carla H.; Olsen, Karina Standahl; Skeie, Guri; Lasheras, Cristina; Agudo, Antonio; Rodrigues-Barranco, Miguel; Sánchez, Maria-José; Amiano, Pilar; Chirlaque, María-Dolores; Barricarte, Aurelio; Drake, Isabel; Ericson, Ulrika; Johansson, Ingegerd; Winkvist, Anna; Key, Tim; Freisling, Heinz; His, Mathilde; Huybrechts, Inge; Christakoudi, Sofia; Ellingjord-Dale, Merete; Riboli, Elio; Tsilidis, Konstantinos K.; Tzoulaki, Ioanna (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-13)
      <i>Background</i> - Several dietary factors have been reported to be associated with risk of breast cancer, but to date, unequivocal evidence only exists for alcohol consumption. We sought to systematically assess the association between intake of 92 foods and nutrients and breast cancer risk using a nutrient-wide association study.<p> <p><i>Methods</i> - Using data from 272,098 women ...

    • A Prospective Diet-Wide Association Study for Risk of Colorectal Cancer in EPIC 

      Papadimitriou, Nikos; Bouras, Emmanouil; van den Brandt, Piet A.; Muller, David C.; Papadopoulou, Areti; Heath, Alicia K.; Critselis, Elena; Gunter, Marc; Vineis, Paolo; Ferrari, Pietro; Weiderpass, Elisabete; Boeing, Heiner; Bastide, Nadia; Merritt, Melissa A.; Lopez, David S.; Bergmann, Manuela M.; Perez-Cornago, Aurora; Schulze, Matthias; Skeie, Guri; Srour, Bernard; Eriksen, Anne Kirstine; Boden, Stina; Johansson, Ingegerd; Nøst, Therese Haugdahl; Lukic, Marko; Ricceri, Fulvio; Ericson, Ulrika; Huerta, José-Maria; Dahm, Christina C.; Agnoli, Claudia; Amiano, Pilar; Tjønneland, Anne; Barricarte, Aurelio; Bueno-de-Mesquita, Bas; Ardanaz, Eva; Berntsson, Jonna; Sánchez, Maria-Jose; Tumino, Rosario; Panico, Salvatore; Katzke, Verena; Jakszyn, Paula; Masala, Giovanna; Derksen, Jeroen W.G.; Quirós, J. Ramón; Severi, Gianluca; Cross, Amanda J.; Riboli, Ellio; Tzoulaki, Ioanna; Tsilidis, Konstantinos K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-24)
      Background & Aims - Evidence regarding the association of dietary exposures with colorectal cancer (CRC) risk is not consistent with a few exceptions. Therefore, we conducted a diet-wide association study (DWAS) in the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate the associations between several dietary exposures with CRC risk.<p> <p>Methods - The association ...

    • Risk prediction for estrogen receptor-specific breast cancers in two large prospective cohorts 

      Li, Kuanrong; Anderson, Garnet; Viallon, Vivian; Arveux, Patrick; Kvaskoff, Marina; Fournier, Agnès; Krogh, Vittorio; Tumino, Rosario; Sánchez, María-José; Ardanaz, Eva; Chirlaque, Maria-Dolores; Agudo, Antonio; Muller, David C.; Smith, Todd; Tzoulaki, Ioanna; Key, Timothy J.; Bueno-de-Mesquita, Hendrik Bastiaan; Trichopoulou, Antonia; Bamia, Christina; Orfanos, Philippos; Kaaks, Rudolf; Hüsing, Anika; Fortner, Renée T.; Zeleniuch-Jacquotte, Anne; Sund, Malin; Dahm, Christina C; Overvad, Kim; Aune, Dagfinn; Weiderpass, Elisabete; Romieu, Isabelle; Riboli, Elio; Gunter, Marc J.; Dossus, Laure; Prentice, Ross; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-03)
      <p><i>Background</i>: Few published breast cancer (BC) risk prediction models consider the heterogeneity of predictor variables between estrogen-receptor positive (ER+) and negative (ER-) tumors. Using data from two large cohorts, we examined whether modeling this heterogeneity could improve prediction.</p> <p><i>Methods</i>: We built two models, for ER+ (Model<sub>ER+</sub>) and ER- tumors ...